Caitlin Shepard Selected Research

SAM Domain and HD Domain-Containing Protein 1

1/2022	Elimination of Aicardi-Goutières syndrome protein SAMHD1 activates cellular innate immunity and suppresses SARS-CoV-2 replication.
10/2021	Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.

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Caitlin Shepard Research Topics

Disease

4	Infections 01/2022 - 01/2016
2	Neoplasms (Cancer) 10/2021 - 01/2020
1	Viremia 01/2022
1	Starvation 01/2018
1	Hypersensitivity (Allergy) 08/2017

Drug/Important Bio-Agent (IBA)

3	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2017
2	Antiviral Agents (Antivirals)IBA 01/2022 - 01/2018
2	SAM Domain and HD Domain-Containing Protein 1IBA 01/2022 - 10/2021
2	Proteins (Proteins, Gene)FDA Link 10/2021 - 01/2016
1	InterferonsIBA 01/2022
1	Viral ProteinsIBA 01/2022
1	EnzymesIBA 10/2021
1	Aspartic Acid (Aspartate)FDA Link 10/2021
1	Histidine (L-Histidine)FDA Link 10/2021
1	Biomarkers (Surrogate Marker)IBA 10/2021
1	dihydromyricetinIBA 01/2020
1	pyrimidineIBA 01/2020
1	ZincIBA 01/2020
1	dihydropyrimidinaseIBA 01/2020
1	dihydrouracilIBA 01/2020
1	Cyclin A2IBA 01/2018
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 08/2017
1	NucleosidesIBA 01/2017